Performs Filtration and Drying of Lab-Scale Batches

The GFD®Lab, brought to you by Powder Systems Limited (PSL), is a benchtop agitated nutsche filter dryer designed to revolutionize laboratory-scale solid-liquid separation and drying. It combines filtration, washing, re-slurry, vacuum drying, and discharge processes within a single compact unit, making it an essential tool for research institutes, laboratories, and educational institutions. Engineered for flexibility, the GFD®Lab accommodates interchangeable vessels of borosilicate glass, stainless steel, or Alloy-22, ensuring chemical compatibility across various applications such as pharmaceuticals, biotechnology, and chemical process development. The modular design allows easy upgrades to the GFD®Lab PLUS, featuring advanced automation with digital touchscreen controls and real-time data monitoring to enhance process optimization. With its unique filtration basket that facilitates maximal product recovery and adaptability for multi-product use, the GFD®Lab ensures consistent and reproducible results. It supports regulatory needs by meeting Good Laboratory Practices (GLP) and offers seamless integration for scale-up activities, making it ideal for producing antibiotic compounds, APIs, vitamins, and custom chemical compounds.

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Performs Filtration, Drying, and Product Recovery

The GFD® Pilot Nutsche Filter Dryer from PSL is an engineered solution designed for precise solid-liquid separation and drying processes, essential in pharmaceuticals and fine chemicals. This compact, mobile unit excels at pilot and R&D scales by combining filtration and drying in one system, overcoming traditional challenges like inefficient recovery. Its agitated vessel works under vacuum and pressure, maximizing the yield of solids while ensuring thorough drying, facilitated by a heated jacket. The removable filtration basket allows easy product recovery and changeover for diverse applications, ranging from active pharmaceutical ingredients to specialty chemicals. Designed for flexibility, it supports multiple materials like Borosilicate 3.3 glass and 316L stainless steel to meet various chemical compatibility requirements. With hazardous area compliance options, including ATEX-certified pneumatic drives, it caters to solvent-based processes safely. It adheres to rigorous standards, complying with Pressure Directives and offering U-Stamp, PED, and SELO certifications. The GFD® Pilot ensures efficient operation within compact spaces like fume cupboards, enhancing its integration into existing systems. Optional GFD® FilterBox containment solutions safeguard both operators and products during handling of toxic materials, reinforcing its role in safe, high-yield production environments.

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Filters and Separates Slurries and Cakes Efficiently

The Multilayer Filter Plate from the HEINKEL Drying & Separation Group is an essential component for Nutsche Filter Dryers, tailored to meet the diverse demands of pharmaceutical, chemical, and food industries. These plates excel in providing precise filtration and separation, utilizing a customizable multi-layer design that supports efficient batch processing of slurries, cakes, and liquids. With applications extending to the production of active pharmaceutical ingredients (APIs), specialty chemicals, and food additives, they ensure reliable performance and longevity.

The plates are offered in a range of materials, including SS 316L and Hastelloy C22, to withstand corrosive environments and backpressure of up to 0.5 bar. Their smooth surfaces and underside mounting facilitate easy cleaning and maintenance, making them ideal for pharmaceutical uses requiring stringent hygiene standards. These plates seamlessly replace existing components, even across different machine brands, and can be divided into sectors, allowing cost-effective maintenance in case of wear or breakage. Their robust design enables the efficient integration into existing lines, ensuring continuous operation and process optimization.

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Filters, Dries, and Mixes Pilot-Scale Products

The COMBER Pressofiltro® / Turbodry® Series PF/TD units by Heinkel are versatile pilot plant filter and vacuum dryers designed for industries such as pharmaceutical, chemical, and food processing. Specially engineered to perform processes like filtration, drying, and mixing, they cater to operations that require small-scale production or pilot testing. This equipment is ideal for end-products like active pharmaceutical ingredients, epoxy resin powder coatings, and synthetic pigments.

Constructed in accordance with the Pressure Equipment Directive 97/23/EG and ASME U-stamp, these units are compliant with GMP and FDA guidelines, ensuring certification for pharmaceutical applications. They operate safely in ATEX danger zones (group II 2G 2D, zones 1/21) thanks to their explosion-protected control system (EEx-d). Built on a skid with a secure shaft seal via a gland nut, they support easy integration within existing production lines.

Customization is available, featuring a multilayer PLC system to enhance automation and process control. This series caters to Research & Development, laboratory, and processing departments seeking efficient filtration and drying of slurry and cake types. The equipment is also engineered for ease of maintenance with its robust design and materials suitable for a range of industrial environments.

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Filters and Dries Slurries in Pilot Batches

The COMBER Pressofiltro® Series PF 5 – PF 100 Pilot Plant units from the HEINKEL Group are designed for precise filtration and drying in pilot and laboratory settings. Engineered to cGMP and FDA guidelines, these units provide versatile processing for pharmaceuticals, chemicals, and food products, converting slurries into dried solids like active pharmaceutical ingredients and specialty chemicals. Each unit employs an efficient filter dryer mechanism, housed in compact skid-mounted systems for easy integration into R&D labs or small-batch production lines.

These pilot units support capacities from 8 to 100 liters and feature interchangeable vessel bases for conversion to conical bottom or Nutsche dryers, enhancing flexibility across applications. The equipment’s heated, stainless steel or Hastelloy contact surfaces ensure uniform drying while resisting corrosion. A PLC-controlled system facilitates automation and seamless integration into existing setups. Customizable options include steam sterilizable and aseptic designs, dust filters, sampling valves, and CIP systems, all of which simplify maintenance and enhance safety and cleanability, making them ideal for moisture-sensitive processes.

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Processes and Sterilizes Slurry into Dry Cake

The COMBER Pressofiltro® Series PF 50 – PF 6000 is a versatile sterilizable agitated Nutsche filter dryer from HEINKEL’s esteemed product line, designed to maintain sterility throughout the filtration, washing, drying, and discharge processes. This equipment excels in applications requiring stringent sterility and cleanliness, such as manufacturing active pharmaceutical ingredients, specialty chemicals, and powdered food additives.

With a filtration area ranging from 0.13 to 6 m², and a slurry volume capacity of 55 to 6,000 liters, the COMBER Pressofiltro® is engineered for both batch and pilot operations. Its PLC-controlled system ensures seamless integration and automation, while compliance with cGMP and FDA guidelines guarantees product safety and quality.

Utilizing a steam sterilizable design, it ensures thorough sterilization, reaching all contact points without air entrapment, and incorporates CIP and SIP systems for automatic, efficient cleaning and disinfecting. Fabricated with materials like stainless steel, Hastelloy, and titanium, it offers excellent corrosion resistance. Moreover, it features an aseptic design with externally interchangeable dry running double mechanical seals.

The versatile COMBER Pressofiltro® comes equipped with options for dust filters, sampling valves, and vacuum systems, supporting tailored engineering to meet specific production needs.

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Ensures Safe Handling and Containment

The Containment System / Glove Box from HEINKEL Drying & Separation Group is designed to enhance safety and efficiency in handling sensitive materials during batch processing. This system effectively isolates operations such as sampling, discharging, and packaging, ensuring both operator safety and product integrity. It is particularly suited for pharmaceutical and chemical industries producing active pharmaceutical ingredients, specialty chemicals, and catalysts.

The glove box operates by creating a sealed environment, preventing contamination with its flange-connected isolator, ideal for integration with Nutsche filter dryers. While handling solids, powders, and cakes, it allows full product yield by facilitating the discharge of residual heel and safe disposal of filter cloths.

For those prioritizing operational efficiency, this system seamlessly integrates into your production line with manual batch operations. The containment system is manufactured with corrosion-resistant materials, offering customization options to meet specific industry compliance standards such as GMP and FDA. Designed for reliability and ease of maintenance, it supports safe disposal processes and complete protection of both product and staff within pharmaceutical, chemical, and metal recycling applications.

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Filters, Dries, and Separates Solid and Slurry Products

The Pressofiltro® Series PF 2000 – PF 16000 from COMBER is a versatile filter dryer designed for pharmaceutical, chemical, and food product manufacturers. This equipment combines filtration and drying processes within a closed unit, optimizing production efficiency and reducing contamination risks. Its unique agitator blade design ensures effective and even product movement during the drying process, while the narrow agitator-to-wall clearances enhance emptying characteristics. Suitable for both batch and continuous operations, it handles solid, powder, slurry, and cake products, making it ideal for producing APIs, chemical intermediates, or powdered metals. With a control cabinet featuring PLC and HMI, it supports seamless integration with existing production lines. Constructed from materials like stainless steel and Hastelloy, it offers excellent corrosion resistance for handling aggressive substances. Certified for operation under the EU-Type Examination Certificate and capable of UL-approved installations, it meets high safety standards. The inclusion of a CIP system ensures thorough, contamination-free cleaning, making maintenance efficient while minimizing downtime.

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Filters, Dries, and Contains Hazardous Materials

The COMBER Pressofiltro® Series PF 50 – PF 2000 is an engineered solution from HEINKEL Group designed to meet rigorous industrial requirements for filtration and drying. Unique in its integration of an agitated Nutsche filter with a containment system, it addresses the high-stakes challenge of handling hazardous materials safely. Utilizing containment glove boxes, it ensures contamination-free product handling, crucial for maintaining purity in pharmaceutical ingredients and specialty chemicals.

The system supports operations such as batch or continuous processing for a variety of materials, including slurries and cakes. It features variable design capacities from 0.13 to 2 m² filter area and slurry volumes ranging from 55 to 2,000 liters. Engineered to adhere to cGMP and FDA guidelines, it employs HEPA-filtered air handling to maintain containment levels down to 10 ng/m³ TWA.

Constructed with high-grade materials like stainless steel and Hastelloy, it offers exceptional resistance to corrosive substances. The system’s automated features include a PLC-controlled interface, enabling seamless integration with existing production lines. Enhanced by options like dust filters, CIP systems, and vacuum units, the COMBER Pressofiltro® ensures both efficiency and safety in demanding applications.

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Performs Filtration, Drying, and Inspection

The COMBER Pressofiltro® Series PF 100 – PF 10000 is designed for multipurpose production facilities in pharmaceutical and chemical industries. Featuring a robust agitation mechanism for efficient slurry processing, it caters to the filtration and drying needs of APIs, specialty chemicals, and nutraceutical powders, ensuring precise moisture control. With a modular design, it accommodates a range of slurry volumes from 100 to 10,000 liters, offering seamless integration into both batch and continuous operations. Constructed with high-grade stainless steel and options for nickel-based alloys, it guarantees corrosion resistance, aligning with stringent cGMP and FDA standards. The system incorporates automated CIP processes for superior cleanability, minimizing contamination risk and downtime. The PLC-controlled unit is equipped with HMI touchscreens for intuitive operation and can integrate with DCS for enhanced process management.

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