Grinds and Disperses Particles in Liquid Solutions

The MicroMedia+ from Bühler Group is a high-performance bead mill designed to tackle the challenges of fine grinding and dispersing in demanding applications. Its innovative engineering allows for effective particle size reduction, ensuring uniform distribution in end products such as packaging labels, OLED displays, and lithium-ion batteries. Utilizing a sophisticated bead separation system, it supports continuous and automated operations with high energy efficiency, reducing energy consumption while maintaining optimal output. The equipment excels in integrating into existing processing lines, offering centralized control options and IoT readiness for seamless monitoring and adjustments. Available in various materials to ensure chemical compatibility, the MicroMedia+ also features a redesigned bearing unit and lifting device for straightforward cleaning and maintenance, minimizing downtime. Whether you manufacture chemicals, cosmetics, or electronic materials, this bead mill provides tailored solutions for your most exacting production needs.

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Grinds and Disperses Materials Efficiently

The Centex Full-volume Bead Mill from Bühler Group revolutionizes wet grinding and dispersing with its advanced design tailored for high-demand industries such as printing inks, paints, coatings, chemicals, and cosmetics. Utilizing reverse-feeding EcoMizer agitator disks, it achieves a homogenous bead distribution, enhancing energy efficiency and reducing grinding costs. Capable of processing various liquid and slurry compositions, it is ideal for producing pigment dispersion inks, automotive paints, epoxy coatings, and more. The mill’s large screen surface and sophisticated bead separation system ensure high throughput and minimal temperature issues. Fully automated with touch screen controls, it offers seamless integration into continuous high-speed operations. Available in materials compatible with chemical and corrosion resistance needs, the Centex offers customizable configurations and engineering support to fit specific plant requirements, optimizing both performance and cost efficiency.

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Coats Tablets with Precision and Consistency

The Thomas Perforated Coating Machine, available through AUSTAR, revolutionizes tablet coating processes with its innovative design. This machine features automatic control and batch management capabilities, utilizing the TAAC software model to optimize economic benefits while maintaining stable process conditions. The replaceable coating pan design offers flexibility for research, pilot testing, and full-scale production, accommodating various batch sizes and product types.

The coating machine excels in creating uniform coatings on pharmaceutical, health care, and food tablets, ensuring quality across products like pain relief and multivitamin tablets. The cylindrical pan maximizes coating area, enhancing efficiency and uniformity, while the spiral-type stirring paddle ensures effective mixing, even for tablets with lower hardness.

With its bypass design for process air intake and central tube spray boom technology, the machine minimizes disturbances, ensuring a stable coating environment. It supports high containment operations at OEB3-OEB5 levels, making it suitable for highly toxic and active products. Additionally, the machine is engineered for energy efficiency and integrates seamlessly into existing production lines with its advanced automation capabilities.

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Produces High-Purity Water for Injection

AUSTAR’s Full-Membrane WFI Generation System is engineered to meet the rigorous demands of pharmaceutical and biotechnology sectors. This system uniquely combines full-membrane technology with a multi-stage purification process to produce high-purity water for injection, crucial for sterile and non-sterile API production. The system’s automation and PLC integration facilitate seamless operation within complex production lines, while its high throughput capability ensures efficient water production suitable for scales from laboratory to industrial. Built with durable stainless steel, it resists corrosion and is compatible with harsh chemicals. It complies with GMP and FDA standards, with integrated CIP systems for streamlined maintenance, making it ideal for manufacturing monoclonal antibodies, vaccines, and various pharmaceutical formulations. Customization options are available, backed by comprehensive engineering support.

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Ensures Containment and Sterile Material Transfer

The High Containment Isolator System from AUSTAR is designed to provide unparalleled protection and sterility for handling high potency and toxic pharmaceutical materials. Utilizing adjustable positive or negative pressure environments, this isolator offers a controlled atmosphere for sensitive operations, ensuring operator safety and product integrity. Equipped with HEPA filters for air inlet and exhaust, it achieves efficient air filtration and laminar flow, crucial for sterile processing. It seamlessly integrates with various material transfer systems, such as Rapid Transfer Ports and split butterfly valves, for secure handling. Ideal for applications in manufacturing pharmaceutical tablets, biopharmaceuticals, and cancer treatment drugs, it supports operations from OEB3 to OEB5 containment levels. The isolator is fully customizable to accommodate specific client needs and is accompanied by AUSTAR’s SMEPAC testing service, ensuring compliance with stringent containment requirements. Constructed with high-quality materials for chemical resistance and durability, it meets GMP and FDA standards, and facilitates easy maintenance through safe filter replacements and ergonomic designs.

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Micronizes Powders and Reduces Particle Size

The Jet Mill from AUSTAR is a precision-engineered solution tailored for micronizing pharmaceutical powders and fine chemicals, utilizing Swiss Schedio SA’s advanced technology. This equipment employs high-pressure airflow to drive particle collision, friction, and shear, effectively reducing particle size to less than 10 microns, essential for consistent quality in pharmaceutical ingredients and specialty chemicals.

Ideal for pharmaceutical and biopharmaceutical applications, the Jet Mill ensures uniform particle distribution for active pharmaceutical ingredients, vaccine adjuvants, and enzyme preparations. It offers a customizable micronizing process to meet varying production capacities and integrates seamlessly into both processing and laboratory environments.

With energy-efficient operations, the Jet Mill minimizes resource consumption while maintaining high throughput. Constructed with materials ensuring superior corrosion resistance, it meets GMP and FDA standards, ensuring compliance for pharmaceutical manufacturing. Its clean-in-place capabilities simplify maintenance, making it a robust choice for those prioritizing efficiency and reliability in powder processing.

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Grinds, Fragments, and Coats for Nano-Scale Precision

The DYNO®-MILL from WAB is a versatile bead mill engineered for wet grinding and nano-processing in the pharmaceutical, biopharmaceutical, and chemical industries. It stands out by offering both continuous and discontinuous operation modes, facilitated by easily interchangeable grinding containers. With the option to use the KD agitator discs or the DYNO-ACCELERATOR, it adapts seamlessly to various production requirements, allowing for easy scalability from laboratory to full-scale production. This equipment is ideal for grinding applications involving cell fragmentation, soft capsules, and coating materials.

The DYNO®-MILL can handle various product types including liquids, slurries, powders, and solids, with a design that ensures no metal contamination thanks to high-quality ceramic components like SiC and ZrO2. Its efficient cooling properties make it suitable for processing temperature-sensitive materials. The mill features a GMP-compliant design, ensuring it meets stringent pharmaceutical standards, and its construction supports effortless cleaning, facilitating a contamination-free environment. The intuitive control system, WAB VIEW, enables precise monitoring and control, allowing integration into broader automated systems. For added customization, you can choose from components made of hardened steel, stainless steel, or advanced ceramics, ensuring the mill matches your specific material needs.

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Crushes and Sieves for Precise Particle Control

The AUSMILL series from AUSTAR offers specialized hammer, cone, and centrifugal sieve mills designed for precise particle size control across pharmaceutical, food, and fine chemical industries. These mills efficiently crush and sieve a wide range of materials, utilizing a star-type valve for dust-free operation and customizable screen sizes ranging from 0.2 to 10 mm. The HMA series hammer mills feature dual-action rotors—one side for crystalline materials and the other for fibrous substances—with integrated temperature monitoring and cavity cooling for minimal heat impact. The CMA cone mills are ideal for viscous materials with a beveled or rounded rotor to prevent bridging and ensure smooth operation. For high-capacity needs, the SCMA centrifugal sieve mills offer an innovative sieving method to maintain low temperature rises, perfect for heat-sensitive products. With capabilities like CIP/SIP for easy cleaning and real-time process monitoring via a control system, these mills support various end-products like tablets, nutraceutical powders, and seasoning blends while ensuring compliance with industry standards. Customizable configurations and engineering support make the AUSMILL an adaptable choice for specific production needs.

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Granulates and Coats Pharmaceutical Powders and Pellets

AUSTAR’s Wet Granulating System, featuring high shear granulators and fluid bed processors, excels in precision pharmaceutical granulation and pellet coating. This system integrates process analytical technology (PAT) and automatic control systems ensuring consistent granule size and coating evenness for high-potency APIs and complex formulations. It caters to immediate and extended-release tablets, effervescent formulations, and enteric-coated pellets, handling both batch and continuous operations with high-speed processing capabilities.

Engineered for seamless integration within existing production lines, it supports batch management, electronic record-keeping, and data integrity in compliance with FDA, EMA, and WHO standards. Available in stainless steel, the equipment meets strict GMP and regulatory requirements, offering high corrosion resistance and robust material options. The modular design ensures easy cleaning and maintenance, supported by an experienced after-sales service team for ongoing operational efficiency and compliance verification. With customizable configurations and expert engineering support, the system ensures precise, high-quality production tailored to pharmaceutical and biotech needs.

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Processes Pharmaceutical Powders and Granules

The ZSE 12 HP-PH twin-screw extruder from Leistritz, offered by AUSTAR, is engineered specifically for the pharmaceutical industry, making it a standout in high-containment production environments. This equipment utilizes a high-torque spline shaft with flexible screw elements to handle processes like hot-melt extrusion and wet granulation efficiently. Adaptable to continuous operations, the extruder ensures stable temperature control and precise mixing, vital for producing solid oral dosage forms, transdermal patches, and other solubility-enhanced drug compounds. Its design supports complex processes with a broad processing window, catering to R&D and large-scale production needs. Available with compliance to GMP and FDA standards, it facilitates seamless integration into existing production lines, enhancing both productivity and safety. The extruder’s maintenance benefits from its easy access for cleaning and optional CIP system, while customization options are available to tailor torque and process capabilities to specific pharmaceutical applications.

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