Performs Filtration, Drying, and Product Recovery

The GFD® Pilot Nutsche Filter Dryer from PSL is an engineered solution designed for precise solid-liquid separation and drying processes, essential in pharmaceuticals and fine chemicals. This compact, mobile unit excels at pilot and R&D scales by combining filtration and drying in one system, overcoming traditional challenges like inefficient recovery. Its agitated vessel works under vacuum and pressure, maximizing the yield of solids while ensuring thorough drying, facilitated by a heated jacket. The removable filtration basket allows easy product recovery and changeover for diverse applications, ranging from active pharmaceutical ingredients to specialty chemicals. Designed for flexibility, it supports multiple materials like Borosilicate 3.3 glass and 316L stainless steel to meet various chemical compatibility requirements. With hazardous area compliance options, including ATEX-certified pneumatic drives, it caters to solvent-based processes safely. It adheres to rigorous standards, complying with Pressure Directives and offering U-Stamp, PED, and SELO certifications. The GFD® Pilot ensures efficient operation within compact spaces like fume cupboards, enhancing its integration into existing systems. Optional GFD® FilterBox containment solutions safeguard both operators and products during handling of toxic materials, reinforcing its role in safe, high-yield production environments.

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Filters, Dries, and Processes Slurry for Pharmaceuticals

The SimpleFilter™ from Powder Systems Limited is an engineered solution for small scale and pilot batch processing in pharmaceutical, chemical, and biotech industries. This Nutsche filter dryer stands out with its compact, mobile design allowing for efficient filtration, drying, and washing of slurries, cakes, and solids. Its single plate pressure and vacuum vessel integrates a glove-bag containment system, ensuring safe discharge and sampling under a nitrogen purge. Available in 316L stainless steel or PFA-coated options, it offers significant corrosion resistance. The system is designed for GMP compliance, supporting applications such as API purification, specialty chemicals, and biopharmaceuticals. With vessel volumes ranging from 50 to 130 liters and configurable with agitation and CIP systems, SimpleFilter™ enhances adaptability and production agility, ensuring high product recovery and maintaining crucial process parameters consistent from R&D to commercial production stages.

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Facilitates Filtration, Re-Slurry, and Vacuum Drying

The Agitated Nutsche Filter Dryer (ANFD) from Powder Systems Limited is an integrated filtration and drying system designed for the complexities of chemical synthesis processes. It features an agitated vessel capable of operating under both vacuum and pressure, ensuring efficient product drying and mixing. Ideal for pharmaceutical, fine chemical, and precious metal industries, it supports operations like washing, re-slurrying, and vacuum drying to produce high-purity Active Pharmaceutical Ingredients (APIs) and other compounds. The system’s modular design allows for vessel fabrication in stainless steel or Alloy 22, with options for PFA coating to enhance corrosion resistance. Additionally, it complies with strict cGMP and FDA standards, ensuring safe processing of highly potent compounds. Its automated systems integrate seamlessly into existing production lines, supporting batch and continuous operations with high containment capabilities. Designed for ease of maintenance, the ANFD includes features for simple cleaning and product discharge, helping optimize production yield through its Direct Heel Recovery method.

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Performs Filtration and Drying of Lab-Scale Batches

The GFD®Lab, brought to you by Powder Systems Limited (PSL), is a benchtop agitated nutsche filter dryer designed to revolutionize laboratory-scale solid-liquid separation and drying. It combines filtration, washing, re-slurry, vacuum drying, and discharge processes within a single compact unit, making it an essential tool for research institutes, laboratories, and educational institutions. Engineered for flexibility, the GFD®Lab accommodates interchangeable vessels of borosilicate glass, stainless steel, or Alloy-22, ensuring chemical compatibility across various applications such as pharmaceuticals, biotechnology, and chemical process development. The modular design allows easy upgrades to the GFD®Lab PLUS, featuring advanced automation with digital touchscreen controls and real-time data monitoring to enhance process optimization. With its unique filtration basket that facilitates maximal product recovery and adaptability for multi-product use, the GFD®Lab ensures consistent and reproducible results. It supports regulatory needs by meeting Good Laboratory Practices (GLP) and offers seamless integration for scale-up activities, making it ideal for producing antibiotic compounds, APIs, vitamins, and custom chemical compounds.

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Processes and Sterilizes Slurry into Dry Cake

The COMBER Pressofiltro® Series PF 50 – PF 6000 is a versatile sterilizable agitated Nutsche filter dryer from HEINKEL’s esteemed product line, designed to maintain sterility throughout the filtration, washing, drying, and discharge processes. This equipment excels in applications requiring stringent sterility and cleanliness, such as manufacturing active pharmaceutical ingredients, specialty chemicals, and powdered food additives.

With a filtration area ranging from 0.13 to 6 m², and a slurry volume capacity of 55 to 6,000 liters, the COMBER Pressofiltro® is engineered for both batch and pilot operations. Its PLC-controlled system ensures seamless integration and automation, while compliance with cGMP and FDA guidelines guarantees product safety and quality.

Utilizing a steam sterilizable design, it ensures thorough sterilization, reaching all contact points without air entrapment, and incorporates CIP and SIP systems for automatic, efficient cleaning and disinfecting. Fabricated with materials like stainless steel, Hastelloy, and titanium, it offers excellent corrosion resistance. Moreover, it features an aseptic design with externally interchangeable dry running double mechanical seals.

The versatile COMBER Pressofiltro® comes equipped with options for dust filters, sampling valves, and vacuum systems, supporting tailored engineering to meet specific production needs.

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Performs Filtration, Drying, and Separation Operations

The MAVAZWAG® Agitated Nutsche Filters and Filter Dryers from GMM Pfaudler are versatile units designed for efficient batch operations in the pharmaceutical and chemical sectors. These systems excel in deep bed solid-liquid separation, using a specialized filter media to achieve comprehensive drying and discharge. Ideal for applications like antibiotics, APIs, and vaccine intermediates, MAVAZWAG® units integrate seamlessly into production lines with automation systems and CIP/SIP capabilities. Compact and adaptable, they are available in stainless steel, Hastelloy, and glass-lined options to ensure compatibility with corrosive environments. These units comply with GMP standards and offer advanced vacuum and solvent recovery systems, thus enhancing operational efficiency and safety. The unique “Clean Sweep” design facilitates total product discharge, while options for pilot unit testing ensure precise process optimization.

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Performs Filtration, Separation, and Vacuum Drying

The Nutsche Filter Dryer (FNB-S) by Bachiller combines agitated pressure filtration and vacuum drying to meet demanding solid-liquid separation needs, especially in pharmaceuticals and fine chemicals. Its hermetic design prevents contamination, making it ideal for hazardous materials. Operating under pressures up to 3 bar(g) and temperatures up to 200°C, this equipment supports reactions, drying, and cake washing in batch modes. Its versatile filtering surface ranges from 0.07m² to 15m², with capacities from 19L up to 15,000L, catering to various production scales. Constructed from durable materials like Hastelloy, and compliant with cGMP and EHEDG standards, it ensures purity while minimizing waste. The FNB-S integrates smoothly into production lines with automation options and energy-efficient features, supported by CIP/SIP systems for streamlined cleaning. Optional mirror polishing and electro-polishing enhance its corrosion resistance, while hardware and software control options offer precise process management.

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