Fills, Seals, and Stoppers Vials, Syringes, and Cartridges

The TRUKING Flextron Series Nest Fillers are designed to meet the diverse challenges faced by modern pharmaceutical manufacturers. This equipment facilitates the seamless filling, sealing, and stoppering of vials, pre-filled syringes, and cartridges. Utilizing a fully servo-controlled and robotic design, it ensures high throughput with minimal breakage, processing up to 36,000 units per hour. Its versatility enables handling multiple formats in a single unit, optimizing efficiency across various formulations including biologics and IV solutions.

Automation is enhanced with features like automatic de-bagging and vacuum stoppering, promising precise and bubble-free end products. The system offers in-house OEL 5 containment within custom C-RABS and Isolators for maximum safety and compliance with stringent GAMP, cGMP, and FDA standards. An industrial PC controls operations, ensuring comprehensive data integrity and remote access.

Construction incorporates superior SS 316L for product contact parts, enabling effective cleaning with built-in CIP & SIP systems. Customizable footprints and modular designs are available to fit specific cleanroom requirements, providing an ideal solution for biopharmaceutical applications, including insulin and vaccine production. The TRUKING Flextron Series does more than fill—it integrates performance with compliance, efficiency with precision.

The post Nested fillers for vials, pre-filled syringes, and cartridges appeared first on Making.com.

Removes Pyrogens and Sterilizes Containers

The TRUKING Depyrogenization Tunnel is an essential solution for aseptic processing needs, leveraging advanced sterilization expertise to ensure optimal pyrogen removal. This cutting-edge tunnel utilizes state-of-the-art sterilization techniques, including a validated pressure differential system to maintain sterile conditions throughout the process. Designed to support biopharmaceutical and pharmaceutical tablet production, it ensures sterile manufacture of products like prefilled syringes, ampoules, and intravenous therapy bags.

Featuring a unique CNC-designed mesh belt and an auto wash-in-place system, it offers automatic cleaning and long-term operational reliability. With precise HEPA filter loading and negative pressure diversion technology, contaminant prevention is guaranteed. The tunnel supports automation and integration through IPC control, enabling audit trails and data integrity features compliant with 21 CFR Part 11.

Engineered for energy efficiency, the tunnel minimizes utility usage while maintaining strict compliance with GAMP, cGMP, and FDA regulations. It comes ready for customization with various material options, suited for diverse chemical processing environments, ensuring long-lasting performance and reducing maintenance downtime.

The post Sterilizing and depyrogenization tunnel for ampoules appeared first on Making.com.

Preserves and Stabilizes Sensitive Pharmaceutical Products

Truking Technology’s Industrial Freeze Dryer is engineered for pharmaceutical and biotech industries, offering a robust solution for moisture removal in sensitive formulations. It operates on a sublimation principle, ensuring reliable preservation of vaccines, antibiotics, and nutraceuticals. With a high-capacity throughput, it streamlines production lines by optimizing energy use through variable-speed motor control, reducing consumption by up to 30%. The system is fully automated with PLC integration, allowing for seamless operation and remote diagnostics. Built with corrosion-resistant stainless steel, it complies with GMP and FDA standards, featuring built-in CIP systems for efficient, contamination-free cleaning. Comprehensive customization options are available, supported by Truking’s expert engineering team for tailored production needs.

The post Stainless steel craft tanks for biopharmaceuticals appeared first on Making.com.

Performs Lyophilization for Biopharmaceutical Applications

The Biopharmaceutical Freeze Dryer System from TRUKING Technology Limited provides an efficient solution for lyophilization in sensitive applications like vaccines and insulin injections. It employs an advanced multi-stage freeze-drying process to ensure precise moisture control. Designed for integration into continuous production lines, the system supports automation with a PLC-controlled interface and remote monitoring. Capable of processing a wide range of product types, it maintains energy efficiency with optimized motor controls. Constructed from corrosion-resistant materials, the system adheres to stringent cGMP and FDA standards. Ease of maintenance is ensured with an integrated CIP system for contamination-free cleaning and custom engineering options available to meet specific throughput and configuration needs.

The post Robotic sterilization logistics system appeared first on Making.com.

Sterilizes Pharmaceutical and Biopharmaceutical Products

The industrial autoclave from TRUKING Technology Limited excels in providing reliable sterilization for pharmaceutical and biopharmaceutical products, ensuring compliance with GMP and FDA standards. This autoclave features real-time F0 value processing, utilizing pressure and temperature data to maintain precise sterilization conditions. Its innovative jacketed chamber design accelerates cooling through PID programming, optimizing energy consumption and maintenance accessibility.

This equipment is engineered to handle a diverse range of products, such as vaccines, lyophilized antibiotics, and traditional herbal extracts. With its automated, continuous operation, the autoclave integrates seamlessly into high-speed production lines. It offers an industrial PC control system, ensuring data integrity and remote access, compliant with 21CFR Part 11.

Manufactured with advanced TIG welding and a mirror-finish chamber, the autoclave resists corrosion and supports various material options for enhanced chemical compatibility. The integrated online sterilization and integrity testing of sterile filters, alongside its unique chamber door sealing for pressure retention, make it a robust choice for high-stakes pharmaceutical manufacturing. TRUKING provides customization options and engineering support to tailor the autoclave to specific production requirements.

The post Superheated water sterilizer for pharmaceutical applications appeared first on Making.com.

Processes and Sterilizes Rubber Stoppers and Caps

The Drum Type Stopper and Cap Processing Machine from TRUKING Technology is designed to meet the demands of aseptic processing in the pharmaceutical industry. This equipment is tailored for the rigorous cleaning, sterilization, and siliconization of rubber stoppers and caps, crucial in the production of vaccines, pre-filled syringes, and BFS containers. Operating with a high-capacity throughput of over 400,000 units per batch, it ensures efficient and precise processing.

The machine employs advanced vacuum-assisted loading, coupled with automatic transfer and bag making systems, for streamlined operations. Its construction features a high-quality TIG-welded chamber with a mirror-polished finish at an Ra ≤0.4µm, enhancing cleaning efficiency and product integrity. The siliconization process is expertly controlled to deliver a uniform layer, optimizing stopper performance in sealing applications.

Control is managed through an industrial PC system, compliant with 21 CFR Part 11, providing features such as audit trail, data integrity, remote access, and real-time monitoring of critical parameters like temperature and pressure. The equipment is constructed from materials compatible with GMP, cGMP, FDA, and other regulatory requirements, ensuring it meets the highest standards in pharmaceutical processing.

Integrated seamlessly into existing production lines, this machine offers a comprehensive solution for pharmaceutical manufacturers and biotech firms, reducing manual interventions and enhancing operational reliability.

The post Washing machine for pharmaceutical rubber stoppers appeared first on Making.com.

Produces Ultra-Pure Water for Manufacturing

The Ultra-Pure Water System from TRUKING Technology is designed to meet the rigorous demands of pharmaceutical and food industries. This system stands out with its modular, tankless design, significantly reducing microbial growth risks while ensuring compliance with GMP and FDA standards. It utilizes an advanced RO-EDI mounting for continuous production, automatically adjusting capacity to accommodate peak loads efficiently. Equipped with an industrial PC for real-time audit trails and data integrity, it boasts a recovery rate exceeding 92%. These systems are crafted with corrosion-resistant materials and offer engineering support for custom configurations based on specific water quality requirements, ensuring seamless integration into existing production lines.

The post Ultra-pure water preparation system for pharmaceutical industry appeared first on Making.com.

Controls Ultrafiltration and Concentration Processes

The AutoTFF series from TRUKING TECHNOLOGY LIMITED is designed for precise ultrafiltration and concentration of pharmaceutical products. This system uniquely incorporates flow feedback control and automated TMP management, ensuring consistent processing across a range of applications such as vaccine production, monoclonal antibodies, and liquid-filled ampoules. With the capability to handle both pilot and full-scale production, it integrates smoothly into existing lines with PLC control and real-time data recording. Energy efficiency is enhanced with an optimized rotor pump system. The equipment is constructed from corrosion-resistant materials, ensuring long-lasting performance and compliance with FDA and GMP standards for pharmaceutical applications. Maintenance is streamlined with an integrated CIP system, allowing quick and efficient cleaning between batches. Customization options allow adaptation to specific production needs, supported by TRUKING’s engineering and technical expertise.

The post Production-level ultrafiltration system for industrial applications appeared first on Making.com.

Controls and Optimizes Bioprocesses for Drug Production

TRUKING’s Bioreactor System provides pharmaceutical and biotech companies with precise control over bioprocesses such as cell culture, fermentation, and bioreaction, critical for producing vaccines, monoclonal antibodies, and genetically engineered drugs. This system offers fully automatic control of parameters like pH, dissolved oxygen, and rate of aeration, coupled with a magnetic suspension stirrer to ensure zero leakage and no contamination. It supports SIP/CIP, enhancing convenience during cleaning and maintenance while ensuring sterility. With a multi-channel capability for aseptic infusion and sampling, this system integrates seamlessly into existing processes. Available in high-grade stainless steel options, it complies with stringent regulatory standards such as GAMP and FDA, ensuring global market readiness. Its industrial PC control system enhances operational monitoring, offering audit trails and data integrity features compliant with 21 CFR Part 11.

The post Bioreactor system for protein and enzyme reaction appeared first on Making.com.

Inspects and Identifies Defects in Pharmaceutical Containers

The Automatic Inspection Machine from Truking Technology Limited is engineered to meet the demanding quality requirements of the pharmaceutical industry. This machine excels in detecting impurities and defects in vials and ampoules by utilizing a servo mechanical system integrated with state-of-the-art software for visual inspections. With a precision tuned to a detectable threshold of 40 μm, it ensures compliance with GAMP, cGMP, and FDA standards. It supports a 360° inspection perspective, capturing high-resolution images across various stations to differentiate between bubbles and particles. The machine also targets cosmetic defects, offering a dedicated collection area for products with only cosmetic issues. Designed for seamless integration into existing production lines, it features an industrial PC for control, complete with features for data integrity and audit trails, complying with 21 CFR Part 11. This system is particularly suitable for producing monoclonal antibodies, vaccines, and pre-filled syringes, among other sensitive pharmaceutical products, and enhances efficiency in high-speed, automated operations.

The post Automatic inspection system for ampoules and vials appeared first on Making.com.