Automates Media Heating, Degassing, and Dispensing

The MP Xtend™ media preparation station from SOTAX revolutionizes the dissolution testing workflow by automating the preparation of dissolution media. This equipment stands out for its ability to consistently heat, degas, and dispense media with precision. Ideal for pharmaceutical, biotech, and chemical industries, it ensures standardized conditions in producing analgesic tablets, vitamin capsules, and various formulations.

The station uses vacuum technology for effective degassing, maintaining USP and FDA-recommended oxygen levels. With a 16-liter capacity, it supports multiple dissolution runs, optimizing throughput in high-speed operations. Full traceability is guaranteed through automated gravimetric volume control and comprehensive audit trails, ensuring compliance with regulatory standards.

Ergonomically designed with the SmartFill™ dispensing head, the MP Xtend™ easily integrates into existing lab setups and minimizes human error. The system supports diverse media, including distilled water, ready-to-use solutions, and concentrated mixtures. An intensive self-cleaning routine ensures easy maintenance and prevents cross-contamination, enhancing operational efficiency.

SOTAX offers extensive customization and engineering support, allowing configurations tailored to specific process needs, while robust materials confer reliable performance in demanding lab environments.

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Automates Dissolution Testing and Provides Real-Time Analysis

The ATF Xtend™ UV Online Dissolution Tester from SOTAX combines full automation with precise UV-Vis analysis, transforming dissolution testing for pharmaceutical manufacturers and R&D laboratories. This system uniquely integrates media preparation, filling, degassing, sampling, and cleaning, ensuring accurate and repeatable results. It suits a wide range of applications, including formulations of tablets, capsules, and semi-solids. The system seamlessly handles tasks like automated vessel filling and filtration, with customizable cleaning routines to support high throughput operations. Material options ensure compatibility with aggressive media, while meeting compliance standards like GMP. With in-built q-doc® software, it guarantees data integrity and regulatory compliance.

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Performs Manual and Semi-Automated Dissolution Testing

The AT Xtend™ Manual Dissolution Tester from SOTAX offers an ideal solution for pharmaceutical manufacturers and research laboratories seeking versatile dissolution testing. This tester features a modular design, allowing seamless transition from manual to semi-automated operation with Xtend™ modules. It supports USP methods 1, 2, 5, and 6, providing precise and repeatable testing for tablets, capsules, and more, with applications spanning pharmaceutical, biotech, and chemical industries. Equipped with a user-friendly touch screen and intuitive EasyTouch™ interface, it simplifies test execution and monitoring. The tester includes options for integrated video monitoring with CenterView™, ensuring comprehensive observation and data recording. Enhanced with automation-ready capabilities, the system allows integration of sampling systems and UV-Vis spectrophotometers, optimizing workflow efficiency. Constructed for robustness, it meets strict pharmacopeial compliance standards, ensuring reliable performance and accurate results.

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Automates Sample Injection into HPLC/UPLC Systems

The ATS Xtend™ LC On-/Offline dissolution tester from SOTAX seamlessly integrates into pharmaceutical and biotech production lines, automating the injection of dissolution samples directly into HPLC/UPLC systems. Its unique ability to simultaneously sample, filter, and inject ensures minimal degradation and high throughput by treating samples with precision down to 0.2-micron filtration. Ideal for a wide range of applications, from aspirin tablets to insulin injectable suspensions, it meets stringent industry requirements while maintaining sample integrity through optional cooling. With flexible integration across various chromatography systems, it supports parallel processing to expedite testing cycles. The system is designed for ease of maintenance, featuring automated cleaning routines to prevent cross-contamination and ensure consistent operation.

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Automates and Analyzes Pharmaceutical Dissolution Testing

The ATS Xtend™ Double UV On-/Offline Dissolution Tester from SOTAX offers an innovative solution for laboratories needing efficient dissolution testing of pharmaceutical and biotech formulations. This system is capable of automating dissolution analysis for up to 16 vessels simultaneously, utilizing high-precision double beam UV-Vis technology for accurate and reliable results. Its standout feature is the ability to alternate between online testing and offline sample collection with minimal system adjustments, enhancing flexibility.

Ideal for analyzing tablets, capsules, injectable suspensions, and other complex drug forms, it supports high-throughput operations to meet demanding production schedules. The Xtend™ system includes robust integration capabilities, sharing a single UV-Vis spectrophotometer and dual-rack sample collector across two dissolution baths, minimizing both financial investment and spatial requirements.

Configured with fully compliant systems that adhere to Pharmacopeia standards and 21 CFR part 11, it ensures stringent regulatory compliance. The equipment’s sampling flexibility, through various filtration methods, optimizes preparation for downstream HPLC/UPLC analysis, while the media and filter stations facilitate precise and efficient media preparation and filtration.

Engineered to reduce variability and improve productivity, the Xtend™ series supports scalable laboratory needs by simplifying the addition of modules without excessive validation requirements. Its compact design allows for easy cleaning and maintenance, further establishing it as an essential tool for pharmaceutical manufacturers and research institutions.

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Conducts Automated Dissolution Testing and UV-Vis Analysis

The AT MD UV On-/Offline from SOTAX is a cutting-edge benchtop dissolution tester offering seamless integration of UV-Vis analysis for comprehensive laboratory applications. This equipment excels in automating dissolution testing processes for pharmaceutical and biotech products, efficiently managing samples from tablets to injectable suspensions. Utilizing a fully automated system, it combines vessel filling, sampling, filtration, and data management into a single process, accommodating both USP basket and paddle methods. The integrated UV-Vis spectrophotometer enables real-time analysis with optional offline sample collection, reducing manual intervention and enhancing productivity. Engineered for regulatory compliance, the AT MD UV offers 21 CFR Part 11 and ALCOA+ data integrity, making it ideal for QC and R&D laboratories. Its compact footprint and robust construction ensure easy placement on standard lab benches, while its modular design supports customized configurations and seamless integration into existing workflows.

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