Facilitates Corrosion-Resistant Chemical Reactions and Mixing

The DIN Glass-Lined Reactors from GMM Pfaudler are engineered for superior corrosion-resistant processing in chemical, pharmaceutical, food, and energy sectors. These reactors follow the DIN 28136 standard, ensuring parts and components interchangeability among manufacturers, which minimizes downtime and dependency on single suppliers. Featuring standardized dimensions and interchangeable components like agitator support flanges, these reactors offer seamless integration with existing systems. They are versatile in applications such as reactions, absorption, distillation, and purification.

The DIN-AE, DIN-BE, and DIN-CE reactor types cater to different capacity needs, from 63 to 80,000 liters. DIN-BE reactors, the most widely used, provide a one-piece design with high pressure resistance and reduced leakage. Equipped with efficient mixing systems, they allow configurations up to seven stages for optimal process adaptation. Maintenance is streamlined with agitator replacements via the manway without extensive disassembly. Compliant with DIN EN ISO 28721-1, these reactors assure stringent enamel quality, meeting or exceeding industry standards. For easy maintenance, these reactors are customizable and supported by engineering expertise, ensuring tailored solutions for various processing demands.

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Distills and Evaporates High-Purity Compounds

GMM Pfaudler’s corrosion-resistant distillation and evaporation system is engineered for efficient separation processes, ideal for chemical, pharmaceutical, food, and energy sectors. Utilizing a versatile design, it handles both batch and continuous operations, catering to solvent recovery and production of high-purity APIs, biofuels, and more. With options for glass-lined reactors and wiped film evaporators, it supports diverse applications from laboratory to full-scale production. Featuring PLC integration for automation and optimized solvent and energy use, the system offers exceptional corrosion resistance, aligned with GMP standards. Customizable to specific requirements, it ensures seamless integration and minimal downtime with its CIP system and robust engineering support.

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Filters, Reacts, and Extracts for Complex Chemical Processes

The Lab Fast Pro Filter-Reactor from NORMAG combines flexibility and efficiency for diverse chemical and pharmaceutical applications. Featuring a universal support frame, it accommodates vessels from 1 to 10 liters, optimizing filtration, reaction, and extraction processes. The system is distinguished by its tool-free clamping mechanism and unique stirrer guide, which ensure easy vessel interchange and minimal wear. PTFE, glass, and PEEK contact materials provide excellent chemical resistance. Ideal for synthesizing peptides, extracting active pharmaceutical ingredients, and processing platinum group metals, it supports both batch and continuous operations. Integration with industry-standard glassware and customizable modules enhances its adaptability for laboratory and R&D environments. Additionally, the reactor’s compliance with stringent pharmaceutical standards ensures high-quality, clean production, while its modular design facilitates straightforward maintenance and cleaning.

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Performs Filtration, Drying, and Mixing Operations

The Filter Dryers MAVALAB from GMM Pfaudler offer a versatile, modular solution for pharmaceutical and chemical industries, prized for efficient solid-liquid separation and drying of active pharmaceutical ingredients and specialized chemical reagents. This mobile unit utilizes a hydraulic-free compact design, enhancing maneuverability in pilot plant settings or low volume production scenarios. Equipped with a purged double mechanical seal and a mechanical speed variator, the MAVALAB allows precise control over the filtration and drying processes, ensuring high-quality product output.

Common applications include laboratory chemical synthesis and pilot-scale drug formulation, addressing challenges in moisture removal and particle sizing. This pre-engineered unit supports integration within existing processing lines, suited for manual operation with full ATEX or NEMA compliant controls, ensuring safe use in explosive environments. The MAVALAB also features WIP/CIP devices for easy, contamination-free cleaning, and its construction in corrosion-resistant materials makes it ideal for handling aggressive substances. Additionally, the unit is adaptable to specific process conditions, backed by GMM Pfaudler’s engineering support for customization.

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Dries and Discharges Sensitive Solid Products

The MAVAPAD® Vacuum Paddle Dryer from GMM Pfaudler offers a robust solution for efficient drying in pharmaceutical, chemical, and food industries. Featuring a large heat transfer area with flat ends, it ensures faster drying and lower heel volumes for challenging applications like APIs and specialty chemicals. The system’s hollow rotating agitator improves heat transfer, and its fully openable door facilitates thorough cleaning and validation. Designed with a choice of stainless steel, Hastelloy, or special alloys, it handles corrosive environments efficiently. The equipment complies with cGMP and FDA guidelines, providing reliable performance in sterile settings. Integration is seamless, utilizing the Dry9000® shaft sealing system to prevent contamination. Optional features like a lump breaker and sampling systems enhance functionality, while the twist close valve ensures quick, residue-free discharge. Tailored engineering support ensures that MAVAPAD® meets specific process needs, promoting operational efficiencies across batch and manual operations.

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Facilitates Mixing and Agitation for Various Industries

The Glass-Lined Mixing and Agitation Systems from GMM Pfaudler are designed for the rigorous demands of chemical, pharmaceutical, and food manufacturing. These systems excel due to their glass-lining technology, providing corrosion resistance and durability in handling aggressive and volatile materials. Operating on a top entry configuration, these systems efficiently facilitate mixing and agitation with reduced vibrations and enhanced operational stability. They are well-suited for producing active pharmaceutical ingredients, specialty chemicals, and biofuels, accommodating both batch and continuous processes. With key features such as a balanced shaft design, motor-driven gear boxes, and absence of bottom bearings, these systems integrate seamlessly into existing production lines. They offer energy-efficient operation with minimal maintenance requirements, and are adaptable to various media and process needs. Additionally, compliance with European Directive 2014/34/EU ensures safe operation in hazardous environments, while the compact design prioritizes ease of maintenance and accessibility for field service teams.

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Processes Corrosive Chemicals and Pharmaceuticals Safely

The ASME RT, RS, RA, and RX series reactors from GMM Pfaudler are engineered to meet the rigorous demands of industries handling corrosive and sensitive materials. These glass-lined reactors offer unparalleled corrosion resistance, leveraging Pfaudler’s glass-lining expertise for enhanced safety in chemical, pharmaceutical, and food processing environments. The reactors feature multi-part or single-piece designs with options for Cryo-Lock technology, which facilitates internal assembly, especially beneficial for applications ranging from active pharmaceutical ingredient production to acid recovery and specialty chemical formulation.

With sizes spanning from 5 to 15,000 gallons, these reactors cater to diverse production scales. The inclusion of the INTERSEAL dry9000® sealing system ensures robust containment and lowers maintenance needs, while the choice of 316L stainless steel base metal in RX series extends their application to ultra-clean environments. Each reactor integrates seamlessly into existing production lines, equipped with advanced automation options and PLC capabilities to enhance efficiency and reduce operational downtime. These reactors are also compliant with ASME codes, providing assurance of safety and reliability in high-pressure scenarios.

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Facilitates Mixing, Reaction, and Thermal Transfer

The Pharma Reactor from De Dietrich Process Systems is designed to enhance efficiency in biopharmaceutical and fine chemical production. It offers unique advantages such as optimized thermal transfer and high agitation performance thanks to the OptiMix® design. The reactor is versatile for producing monoclonal antibodies, APIs, and plant-based extractions. With a capacity range from 63 to 630 liters, it integrates seamless automation via CIP validation ensuring reliable cleaning and reduced downtime. Constructed with glass-lined covers and polished 316L stainless steel components, it offers excellent corrosion resistance and complies with GMP standards. Featuring advanced options like a fused glass quick release, the Pharma Reactor is engineered for flexibility, catering to specific requirements with customizable features and De Dietrich’s comprehensive engineering support.

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Cultivates High-Yield Cell Cultures

The Bioreactor – Fermentor System from De Dietrich Process Systems is engineered for cultivating high-purity biopharmaceutical products. With a borosilicate 3.3 glass construction according to EN1595 standards, its design includes a monobloc inner vessel with a surface finish of ≤ Ra 0.02 μm for optimal cleanliness. Capable of precise agitation and aeration, this system is essential for producing monoclonal antibodies, synthetic peptides, and more. Ideal for operations in R&D labs, biotechnology, and specialty chemicals, it integrates seamlessly into existing processes with various control options, including 21 CFR part 11 interface. The equipment is customizable, offering mechanical or magnetically coupled agitation and stainless steel or alloy components, ensuring compatibility and corrosion resistance. It maintains GMP compliance with complete QA/QC plans, and includes CIP systems for efficient cleaning, making it an indispensable tool for high-stakes production environments.

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Synthesizes, Distills, and Mixes Large-Scale Chemical Reactions

The QVF Universal-Reactor from De Dietrich Process Systems is your go-to solution for scaling up chemical reactions that exceed lab-scale capabilities. Designed for the pharmaceutical, fine chemicals, and specialty chemicals sectors, it allows for precise control in synthesizing active pharmaceutical ingredients, monoclonal antibodies, specialty polymers, and more. By employing a versatile, inert gas-compatible design, this reactor excels in handling liquid and gas processes under vacuum and EX-rated conditions. It facilitates seamless integration into existing lines with its robust, digitally controlled stirrer and OptiMix® baffle system, offering extraordinary mixing performance without splashing. Featuring a borosilicate glass construction and PTFE components, it ensures optimal chemical resistance and longevity. The reactor is equipped with CIP-nozzles, ensuring easy and reliable cleaning between batches, thus minimizing downtime. Compliance with European EX regulations guarantees safe operation in volatile environments. Whether for pilot studies or full-scale production, you can request custom configurations to best meet your specific operational needs.

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