Cleans and Sanitizes Intermediate Bulk Containers

The CONSERVE 360® from ACG is a sophisticated bin washing system designed to meet the stringent cleaning demands of pharmaceutical and nutraceutical manufacturers. It features a crevice-free, double-walled construction that ensures compliance with cGMP standards. The system employs high-pressure jet technology with uniquely designed European nozzles, eliminating dead zones and preventing cross-contamination. It supports user-defined recipe-based cleaning, offering fully automated operation with pre-programmed wash cycles for repeatable results. Significant water savings are achieved, reducing consumption by 60%, and it integrates seamlessly with online conductivity measuring systems for real-time verification and traceability. Built to sustain high water-line pressures, the CONSERVE 360® provides flexibility in pump settings, and its materials offer superior corrosion resistance, making it suitable for a variety of solid pharmaceutical and nutraceutical applications.

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Mixes and Granulates Pharmaceutical Powders

The HSM 1200 High-Shear Mixer from ACG is a critical component for pharmaceutical and nutraceutical manufacturers focusing on efficient granulation and mixing. Designed to handle large production batches, this mixer is known for its superior centrifugal force achieved through a Z-shaped impeller and multi-blade chopper. It ensures uniform binder distribution and optimal particle-size distribution, especially valuable in producing effervescent tablets and protein powders.

Operating with a working volume ranging from 360 to 960 liters, it seamlessly integrates into granulation trains or functions independently, offering flexibility in production lines. Its PLC-controlled system promotes batch operations and high-speed processing, ensuring consistent output. The HSM 1200 reduces energy consumption via optimized motor control and enhances wash-in-place efficiency with integrated cleaning nozzles for swift and dust-free maintenance.

Constructed to adhere to GMP compliance with an ergonomic design, it offers the advantage of easy access for operation and maintenance. With multiple systems for charging and discharging and a highly efficient vent air filtration, the machine supports smooth and uncontaminated processing cycles. Configurations are available to meet your specific operational demands, backed by ACG’s expertise from handling over 1,000 formulations.

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Processes Granulation, Drying, and Coating in One Unit

The FBE 250C, part of ACG’s fluid bed combo series, is designed to address your pharmaceutical and nutraceutical processing needs by combining granulation, drying, and coating processes into one efficient system. Its innovative integration of top-spray and Wurster coating technology enables versatile applications, including the production of tablets, capsules, and powders. With a working capacity of up to 250 liters per batch, it supports various production scales. The machine’s PLC-controlled operations ensure precise process adjustments and seamless integration into production lines. Featuring a state-of-the-art twin-chamber filter bag shaking system, it provides continuous fluidization and reduces compressed air consumption. Constructed with multiple air distribution options and available in corrosion-resistant materials, it meets the rigorous standards of GMP and FDA compliance. Customizable features, including charging, discharging, and wash-in-place systems, coupled with ACG’s engineering support, make it an adaptable choice for diverse manufacturing environments.

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Contains and Packages High-Potency Pharmaceuticals

The SECUREBLIS MINI from ACG is a state-of-the-art containment solution specifically engineered for blister packaging in the pharmaceutical industry. Designed to safely handle highly potent active pharmaceutical ingredients (HPAPIs), it operates under negative pressure environments to minimize operator exposure and ensure compliance with Operational Exposure Band (OEB) 3 standards. The SECUREBLIS MINI is versatile, capable of processing pharmaceutical tablets, hard capsules, and soft gelatine capsules with applications ranging from pain relief to multivitamins.

This machine integrates seamlessly into existing production lines, supporting both thermoforming and cold-forming processes with forming capabilities up to 25 cycles per minute and a maximum forming depth of 12 mm. It features advanced automation, including a wet-in-place (WIP) cleaning system complemented by HEPA filters, which ensures a contaminant-free environment. Its strategic glove ports allow manual interventions without compromising containment, enhancing safety and operational efficiency.

With options to utilize various forming materials, such as PVC and cold-form foil, and lidding materials including child-resistant and tropical foil, the SECUREBLIS MINI offers robust versatility. Its design facilitates fast, safe cleaning and changeovers, reducing downtime and improving throughput. Compliance with GMP and other pharmaceutical standards makes it an ideal solution for companies focusing on regulatory adherence and operator safety.

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Transfers and Synchronizes Powders and Pellets

The Product Conveying System (PCS) from ACG integrates seamlessly into your capsule filling operations, ensuring a consistent and contamination-free transfer of powders and pellets. Utilizing vacuum technology, the PCS efficiently synchronizes with capsule filling machines, preventing material segregation. It is designed for pharmaceutical and nutraceutical industries, handling applications such as conveying and transfer of powders, pellets, nutrients, and supplements. With a throughput of up to 400 liters per hour, it supports high-volume production demands. The PCS is fully automated, cGMP-compliant, and constructed with stainless steel and other food-grade materials to maintain product safety and quality. The system is optimized for quiet operations with the blower strategically separated from the filling area, and it features an additional filter bag to enhance the working environment. This equipment supports ease of maintenance and integration within existing production lines, offering customization options to meet specific operational needs.

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