Acoustic cell retention system

Using high frequency resonant ultrasonic waves to separate cells instead of a physical mesh or membrane, you can have all the benefits from traditional devices without the inherent problems and limitations that come with them.

Non-clogging retention for high-density perfusion processes

The Getinge Applikon BioSep Acoustic cell retention system is a unique, cell retention device for high-density perfusion processes. The BioSep, based on the technology of acoustic resonance, is a non-fouling / non-clogging retention system. The BioSep can be applied in both R&D (max. 1 L/day), process development and on production scale (1000 L/day).


  • Proven under CGMP conditions
  • Easy to install and operate
  • Can be used in combination with any brand of bioreactor
  • Long cultivation possible (>6 months)
  • No fouling or blocking